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Hypertriglyceridemic Waist

MedGen UID:
772447
•Concept ID:
C3658248
•
Sign or Symptom
Synonyms: Enlarged Waist Elevated Triglycerides; Waist, Hypertriglyceridemic

Definition

A screening phenotype consisting of both elevated WAIST CIRCUMFERENCE and elevated fasting TRIGLYCERIDES level. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypertriglyceridemic Waist

Professional guidelines

PubMed

The Metabolic Syndrome Puzzles; Possible Pathogenesis and Management.
Marzoog BA
Curr Diabetes Rev 2023;19(4):e290422204258. doi: 10.2174/1573399818666220429100411. PMID: 35507784
Prevalence and Factors Associated with Metabolic Syndrome in Patients at a Psychosocial Care Center: A Cross-Sectional Study.
Reis da Silva DA, de Almeida LS, Correa LL, Pimentel RFW, Gomes AMT, Travassos AG, Viana AM, Cerqueira MMBDF, de Souza MC, de Sousa AR, Barbosa PJB, Coelho JMF, Magalhães LBNC, D'Oliveira Júnior A, Cavalcante Neto JL, Santos CS, França LCM, Brandão JL, Dos Santos LFM, Gomes HF, Peres EM, Rossi TRA, Damasceno KSM, das Mercês MC, Fernandes SL, Soriano EA, Maduro IPNN, Brandão TS, Menezes AC, Santana AIC, das Merces MC
Int J Environ Res Public Health 2022 Aug 17;19(16) doi: 10.3390/ijerph191610203. PMID: 36011835Free PMC Article
Utility of the hypertriglyceridemic waist phenotype in the cardiometabolic risk assessment of youth stratified by body mass index.
Buchan DS, Boddy LM, Despres JP, Grace FM, Sculthorpe N, Mahoney C, Baker JS
Pediatr Obes 2016 Aug;11(4):292-8. Epub 2015 Aug 7 doi: 10.1111/ijpo.12061. PMID: 26251875

Recent clinical studies

Etiology

Association between hypertriglyceridemic-waist phenotype and circadian syndrome risk: a longitudinal cohort study.
Hu LK, Liu YH, Yang K, Chen N, Ma LL, Yan YX
Hormones (Athens) 2023 Sep;22(3):457-466. Epub 2023 Jul 10 doi: 10.1007/s42000-023-00462-6. PMID: 37423976
Hypertriglyceridemic waist phenotype, hypertriglyceridemic waist-to-height ratio phenotype and abnormal glucose metabolism in adolescents.
Lu N, Cheng G, Ma CM, Liu XL
Diabetes Res Clin Pract 2023 Apr;198:110622. Epub 2023 Mar 15 doi: 10.1016/j.diabres.2023.110622. PMID: 36924832
Association between hypertriglyceridemic waist phenotype and hypogonadism in Taiwanese adult men.
Wang SK, Lee MC, Hung CL, Chen HH, Liao CC, Chiu YL
PLoS One 2022;17(3):e0265629. Epub 2022 Mar 23 doi: 10.1371/journal.pone.0265629. PMID: 35320301Free PMC Article
Hypertriglyceridemic waist phenotype and associated factors in individuals with arterial hypertension and/or diabetes mellitus.
Borges LD, Comini LO, de Oliveira LC, Dias HH, Ferreira ES, Batistelli CRS, da Costa GD, Moreira TR, da Silva RG, Cotta RMM
J Nutr Sci 2021;10:e74. Epub 2021 Sep 14 doi: 10.1017/jns.2021.71. PMID: 34589206Free PMC Article
Metabolic syndrome--practical approach.
Hâncu N, Roman G, Nită C, Negrean M
Rom J Intern Med 2004;42(2):237-45. PMID: 15529614

Diagnosis

Hypertriglyceridemic waist phenotype, hypertriglyceridemic waist-to-height ratio phenotype and abnormal glucose metabolism in adolescents.
Lu N, Cheng G, Ma CM, Liu XL
Diabetes Res Clin Pract 2023 Apr;198:110622. Epub 2023 Mar 15 doi: 10.1016/j.diabres.2023.110622. PMID: 36924832
Association between hypertriglyceridemic-waist phenotype and non-alcoholic fatty liver disease: a general population-based study.
Yang M, Xu Y, Hu C, Zhang S, Kuang M, Zou Y
Lipids Health Dis 2022 Jun 2;21(1):50. doi: 10.1186/s12944-022-01660-8. PMID: 35655216Free PMC Article
The association between hypertriglyceridemic-waist phenotype and chronic kidney disease: a cohort study and meta-analysis.
Chen D, Sun H, Lu C, Chen W, Guo VY
Sci Rep 2022 Feb 4;12(1):1935. doi: 10.1038/s41598-022-05806-7. PMID: 35121773Free PMC Article
Hypertriglyceridemic waist phenotype and associated factors in individuals with arterial hypertension and/or diabetes mellitus.
Borges LD, Comini LO, de Oliveira LC, Dias HH, Ferreira ES, Batistelli CRS, da Costa GD, Moreira TR, da Silva RG, Cotta RMM
J Nutr Sci 2021;10:e74. Epub 2021 Sep 14 doi: 10.1017/jns.2021.71. PMID: 34589206Free PMC Article
Metabolic syndrome--practical approach.
Hâncu N, Roman G, Nită C, Negrean M
Rom J Intern Med 2004;42(2):237-45. PMID: 15529614

Therapy

CD36 polymorphism, sugary drinks, and sedentarism are associated with hypertriglyceridemic waist phenotype.
Navarro-Rios D, Panduro A, Roman S, Ramos-Lopez O
Int J Vitam Nutr Res 2024 Feb;94(1):37-44. Epub 2022 Oct 24 doi: 10.1024/0300-9831/a000771. PMID: 36274589
The relationship between hypertriglyceridemic wait-to-height ratio and hypertension-diabetes comorbidity among older adult.
Zhang P, Xiong Y, Chen M, Zhang H, Sun N, Wu F, Yang J, Ren Y
Front Public Health 2023;11:1292738. Epub 2023 Dec 7 doi: 10.3389/fpubh.2023.1292738. PMID: 38131022Free PMC Article
The association between hypertriglyceridemic-waist phenotype and chronic kidney disease: a cohort study and meta-analysis.
Chen D, Sun H, Lu C, Chen W, Guo VY
Sci Rep 2022 Feb 4;12(1):1935. doi: 10.1038/s41598-022-05806-7. PMID: 35121773Free PMC Article
Relationship between fatty pancreas and hypertriglyceridemic waist phenotype: a cross-sectional study.
Yu X, Wang D, Xiao W, Shi X, She Q, Sun H, Qi T, Xu R, Li G, Liu X, Gong W, Yan Z, Ding Y, Lu G
Sci Rep 2020 Dec 14;10(1):21937. doi: 10.1038/s41598-020-78883-1. PMID: 33318573Free PMC Article
Association Between Lifestyle and Hypertriglyceridemic Waist Phenotype in the PREDIMED-Plus Study.
Fernández-García JC, Muñoz-Garach A, Martínez-González MÁ, Salas-Salvado J, Corella D, Hernáez Á, Romaguera D, Vioque J, Alonso-Gómez ÁM, Wärnberg J, Martínez JA, Serra-Majem L, Estruch R, Lapetra J, Pintó X, Tur JA, Garcia-Rios A, García Molina L, Gaforio JJ, Matía-Martín P, Daimiel L, Martín Sánchez V, Vidal J, Prieto L, Ros E, Goñi N, Babio N, Ortega-Azorin C, Castañer O, Konieczna J, Notario Barandiaran L, Vaquero-Luna J, Benavente-Marín JC, Zulet MA, Sanchez-Villegas A, Sacanella E, Gómez Huelgas R, Miró-Moriano L, Gimenez-Gracia M, Julibert A, Razquin C, Basora J, Portolés O, Goday A, Galmés-Panadés AM, López-García CM, Moreno-Rodriguez A, Toledo E, Díaz-López A, Fitó M, Tinahones FJ, Bernal-López MR; PREDIMED-Plus Investigators
Obesity (Silver Spring) 2020 Mar;28(3):537-543. doi: 10.1002/oby.22728. PMID: 32090511

Prognosis

Association between hypertriglyceridemic-waist phenotype and circadian syndrome risk: a longitudinal cohort study.
Hu LK, Liu YH, Yang K, Chen N, Ma LL, Yan YX
Hormones (Athens) 2023 Sep;22(3):457-466. Epub 2023 Jul 10 doi: 10.1007/s42000-023-00462-6. PMID: 37423976
Relationship Between Hypertriglyceridemic Waist Phenotype and Disposition Index in Chinese Men With Normal Glucose Tolerance.
Liu X, Ma C, Wang R, Lu N, Ma C, Yin F, Lu Q
Am J Mens Health 2023 May-Jun;17(3):15579883231170172. doi: 10.1177/15579883231170172. PMID: 37131294Free PMC Article
Novel lipid indicators and the risk of type 2 diabetes mellitus among Chinese hypertensive patients: findings from the Guangzhou Heart Study.
Deng H, Hu P, Li H, Zhou H, Wu X, Yuan M, Duan X, Lao M, Wu C, Zheng M, Lao XQ, Zhao W, Liu X
Cardiovasc Diabetol 2022 Oct 15;21(1):212. doi: 10.1186/s12933-022-01660-z. PMID: 36243748Free PMC Article
Association between hypertriglyceridemic waist phenotype and hypogonadism in Taiwanese adult men.
Wang SK, Lee MC, Hung CL, Chen HH, Liao CC, Chiu YL
PLoS One 2022;17(3):e0265629. Epub 2022 Mar 23 doi: 10.1371/journal.pone.0265629. PMID: 35320301Free PMC Article
The association between hypertriglyceridemic-waist phenotype and chronic kidney disease: a cohort study and meta-analysis.
Chen D, Sun H, Lu C, Chen W, Guo VY
Sci Rep 2022 Feb 4;12(1):1935. doi: 10.1038/s41598-022-05806-7. PMID: 35121773Free PMC Article

Clinical prediction guides

Association between hypertriglyceridemic-waist phenotype and circadian syndrome risk: a longitudinal cohort study.
Hu LK, Liu YH, Yang K, Chen N, Ma LL, Yan YX
Hormones (Athens) 2023 Sep;22(3):457-466. Epub 2023 Jul 10 doi: 10.1007/s42000-023-00462-6. PMID: 37423976
Association between hypertriglyceridemic waist phenotype and hypogonadism in Taiwanese adult men.
Wang SK, Lee MC, Hung CL, Chen HH, Liao CC, Chiu YL
PLoS One 2022;17(3):e0265629. Epub 2022 Mar 23 doi: 10.1371/journal.pone.0265629. PMID: 35320301Free PMC Article
The association between hypertriglyceridemic-waist phenotype and chronic kidney disease: a cohort study and meta-analysis.
Chen D, Sun H, Lu C, Chen W, Guo VY
Sci Rep 2022 Feb 4;12(1):1935. doi: 10.1038/s41598-022-05806-7. PMID: 35121773Free PMC Article
Cardiovascular Risk in Xavante Indigenous Population.
Soares LP, Fabbro ALD, Silva AS, Sartorelli DS, Franco LF, Kuhn PC, Moises RS, Vieira-Filho JPB, Franco LJ
Arq Bras Cardiol 2018 Jun;110(6):542-550. doi: 10.5935/abc.20180090. PMID: 30226913Free PMC Article
Metabolic syndrome--practical approach.
Hâncu N, Roman G, Nită C, Negrean M
Rom J Intern Med 2004;42(2):237-45. PMID: 15529614

Recent systematic reviews

Hypertriglyceridemic waist phenotype and abnormal glucose metabolism: a system review and meta-analysis.
Ma CM, Liu XL, Lu N, Wang R, Lu Q, Yin FZ
Endocrine 2019 Jun;64(3):469-485. Epub 2019 May 7 doi: 10.1007/s12020-019-01945-6. PMID: 31065910

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